5 Common Peptides Side Effects And Benefits

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Curious about peptide therapy? We’ve listed the most common peptides side effects and uses below.

RELATED: What Are Peptides And Should You Take Them?

In this article:

  1. Collagen Peptides for Aging and Beauty
  2. Creatine Peptides for Strength and Muscle Growth
  3. BPC-157 for Fast Recovery
  4. Follistatin for Muscle Gain and Fat Loss
  5. Milk Peptides for Blood Pressure

5 Peptides Benefits and Side Effects You Should Know About

1. Collagen Peptides for Aging and Beauty

The body produces collagen which keeps our skin, bones, nails, hair, and connective tissues healthy. As we grow older, however, the rate of collagen production slows down resulting in aging and weakening of the joints.

The body requires three amino acids—proline, hydroxyproline, and glycine—to produce collagen, and they’re pretty hard to get from diet. Unless you’re up to the challenge of eating tons of chicken skin or connective tissue, you simply won’t get enough collagen.

Enter collagen supplements—they bring your body the raw materials needed to make its own collagen. As a result, your skin may look smoother and younger, and your joints more flexible as you age.

The best collagen supplements are those hydrolyzed since the body struggles to absorb whole collagen proteins. This means collagen is broken down into collagen peptides for easier absorption.

When buying collagen supplements, look for collagen peptides from grass-fed cows raised organically without hormones and antibiotics.

2. Creatine Peptides for Strength and Muscle Growth

man flexing his muscle | Common Peptides Side Effects And Benefits | FAQs | what are peptides
A man flexing at the gym.

Creatine is a popular fitness supplement that helps with muscle growth and strength improvement.

When lifting weights or running, our strength and endurance eventually drop off a level making the next sets of exercise harder. This is the point where our muscles max out their stored energy (ATP) or the anaerobic threshold.

Creatine can increase the ATP reserve in your muscles and replenish it while you rest. The results include improved strength, endurance, and performance allowing you to finish a few more reps when weight training or last longer in your cardio routine.

Additionally, creatine can also help with muscle building since it can increase protein synthesis and act as a nootropic, improving memory and decreasing mental fatigue.

To enjoy such benefits, you need to first undergo a loading phase where you consume higher amounts of creatine for a week then drop to a maintenance dose. During this loading week, as your body is still adjusting, it’s common to experience short-term side effects like dehydration, nausea, stomachaches, and headaches.

Taking creatine peptides instead can help shorten this loading phase (hence the duration of the annoying side effects, too) because they’re more bioavailable. With creatine peptides, you can cut the loading phase to as short as two to three days.

3. BPC-157 for Fast Recovery

BPC or Body Protecting Compound 157 is also referred to as the Wolverine supplement. Animal research and anecdotal reports on this peptide show its potential capability to heal soft tissue injuries.

Tests on animals showed its healing benefits on muscle injuries, burns, and tendon strains. It was also reported to have been helpful in the growth and regeneration of the subjects’ blood vessels.

Aside from that, this peptide can also reduce oxidative stress risk, the imbalance of free radicals in the body that causes cell damage.

While there are yet to be reported side effects from the studies, we have to note that these tests are done on animals. However, there is a growing number of anecdotal accounts suggesting BPC-157 can manifest the same benefits in humans as that with the animals.

BPC-157 is still new, experimental, and is likely to be classified as a performance-enhancing drug. Use it at your own risk, especially if you are a competitive athlete.

RELATED: Can Peptide Therapy Really Help With Anti-Aging And Skin Rejuvenation?

4. Follistatin for Muscle Gain and Fat Loss

Ever heard about the Belgian Blue cattle? These are unusually muscular cows with a genetic mutation that suppresses the muscle suppressing compound myostatin.

Follistatin is a peptide that naturally mimics what these cows have. It also suppresses myostatin which may lead to impressive muscle gains.

The body produces its own follistatin, but as a supplement, it is fairly new. A study showed that healthy subjects taking follistatin for eight weeks on top of a resistance training program experience tripled muscle growth.

There is animal research, too, reporting that intake of this peptide in rodents resulted in fat loss and muscle gain despite being on a poor diet.

Like BPC-157, this peptide is still experimental. While there’s yet to be an official dose, the usual range is at 100 to 300 micrograms, injected into the area you want to grow and lose fat.

5. Milk Peptides for Blood Pressure

Casein is the main protein in milk that solidifies when it curdles. Our bodies break it down into casein peptides after drinking milk.

Laboratories also create this kind of peptides and market them as dietary supplements for various conditions like hypertension.

While further research is needed to officially prove its effectivity, this literature review affirms its potential therapeutic capabilities.

According to the review, the several milk peptides broken down by digestive enzymes or by lactobacilli-formed proteinases during milk fermentation have shown to have antihypertensive effects in animal and clinical studies.

How Do You Take Peptides?

Most peptides are injected into the body, but experts are now working on other means of taking peptides into the body. Some of the methods include the use of topical creams and patches.

Dr. Seeds has them in supplements.

What Are the Side Effects of Peptides?

If used incorrectly, peptides may induce a couple of side effects of different degrees based on the user. It is best to consult your physician before using them.

Some of the side effects include:

  • Dry mouth
  • Increased water retention
  • Increased hunger
  • Tingling or numbness
  • Itchiness at the injection site
  • Joint pain
  • Weight gain or loss
  • High blood pressure
  • Darkened moles and increasing freckles
  • Decreases fertility
  • Extreme kidney pain

 

Learn the 10 power benefits of peptides from Better Peptides:

It’s only logical to want to know about the side effects of any kind of treatment you might want to try, especially those that are still experimental (like some of the peptides mentioned above). Ultimately, it is always best to make decisions like this with the help of your doctor.

You can’t be too careful anymore, don’t you agree?

Do you have any questions about the side effects of peptides? Let us know in the comments section below!

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